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Nigella sativa Nigella sativa has been used in Iranian traditional medicine for treatment of urinary stones [33,34,78,79]

Clinical experience suggests keeping a simple log during the first six months post-recovery to identify individual sensitivities [1]

Much of the active ingredient is lost during digestion

It exerts an antioxidant function mainly in the form of selenocysteine residues, which are an integral constituent of ROS-detoxifying selenoenzymes, such as GSH-Px, thioredoxin reductases and selenoprotein P

doi: 10.1097/00004703-199906000-00005 8 DrakeCNickelCBurduvaliERothTJeffersonCPietroB

146 Another phase I b clinical trial also showed good tolerability and clinical activity of TelaE or telaglenastat combined with cabozantinib (TelaC) in treating RCC