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Biochem Pharmacol 84:11961206

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By targeting the SASP, senomorphic therapies aim to alleviate the detrimental effects of senescence without necessarily removing the senescent cells.128 This approach provides a novel strategy to mitigate the harmful inflammation, tissue degradation, and chronic diseases associated with cellular senescence, while preserving the beneficial aspects of senescence, such as tumor suppression and tissue repair.129 Overview of Senomorphics Senomorphic agents target the SASP or the molecular pathways that drive it

The infusion must be administered slowly and only by trained clinicians who monitor comfort and response