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In the REDEFINE 2 phase 3a trial involving adults with obesity and diabetes, the use of cagrilintidesemaglutide resulted in a significantly lower body weight than placebo at 68 weeks. Full trial results Novo Nordisk: Can CagriSema Show 25% Weight Loss In REDEFINE 1 Trial? Seeking Alpha Another obesity contender just raised the stakes. Novo Nordisk's CagriSema combination delivered around 20% mean weight loss in a large trial. The formula combines semaglutide with cagrilintide, giving the body multiple appetite control ADA 2025: CagriSema Demonstrates Significant Weight Loss in REDEFINE Clinical Trials Pharmacy Times Trial Scorecard: REDEFINE 1 and 2 Cagrilintide Semaglutide combo Improves Weight Loss and Glycemic Control in T2DM, finds trial
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