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10.1007/bf03160362 124 HansenD

1 In accordance with, but also extending this view, we believe that the balance between distinct immune reactions within one individual is the key to understand the role of IgE armed mast cells in immunoprotection and allergy development

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The mechanism of its pathogenesis is not fully understood, multiple parallel hits are believed to be involved, including insulin resistance, hormones secreted from the adipose tissue, nutritional factors, gut microbiota and genetic and epigenetic factors ( In recent years, more and more attention has been paid to intestinal flora and its metabolites

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