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indeed, 2-DG causes a moderate increase in parasite burden [d4, control parasitemia of 7.83.3% versus 13.33.9% in 2-DG-treated animals, adj

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Hence, Smartamine is resistant to the rumen pH, but is soluble in lower pHs, such as the post-ruminal environment, being undegradable in the rumen and immediately released in the abomasum

However, due to the brains high oxygen consumption and lipid-rich environment, it is particularly vulnerable to oxidative stress when ROS levels exceed antioxidant defenses