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Description

Through experimental methods such as molecular docking, CESTA, and non-targeted metabolomics, we found that SAC can act on the Keap1/Nrf2/GPX4 signaling axis and regulate glutathione metabolism, effectively inhibiting ferroptosis and oxidative damage in colonic epithelial cells, thereby alleviating UC

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The glutathione reductase assay followed the protocol described in ref

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Study on the feasibility of using livestock blood as a fetal bovine serum substitute for cultured meat

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Plant 142 , 339351 (2011)

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Glutathione does not alter tirzepatide's half-life (approximately five days), absorption rate, or receptor binding affinity

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95% CI, 0.614 to 0.325), consistent with the findings from the period effect analysis (Figures 7A,B)

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