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Cell 185, 16941708.e19 (2022)

As the importance of subcellular metabolite transporters in controlling tumor initiation is poorly understood, it would be interesting to determine whether overexpression or knockout of these transporters is involved in tumorigenesis, metastasis, and immune modulation

ROS-Glo H 2 O 2 assay H 2 O 2 induction in HepG2 and HepG2 ATP7B-KO cells after CuCl 2 treatment was performed by ROS-GLO H 2 O 2 Assay (Promega) according to manufacturers instructions

However, future investigations using multiplex or metagenomic approaches are recommended to reveal the full spectrum of enteric pathogens and their interactions