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A.GundayS.IqbalA.AlrushaidN.et al (2022)

The global, regional, and national burden of cancer, 19902023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023

H.MarshD

Fundam Clin Pharmacol 12: 538545

this would allow us to more accurately fit the effect of the drug-induced inhibition of pERK

We generated a combinatorial library by mutating complementarity-determining region (CDR) positions 29 - 32 of CDR-L1, 50 of CDR-L2, and 94 - 96 of CDR-L3, introducing at each explored position amino acid diversity informed by deep mutational scanning previously performed for R023 (Fig