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10.1016/j.phanu.2015.10.001 129

Crucially, in an LPS-induced mouse model of acute lung injury, treatment with compound 25L significantly alleviated pulmonary inflammatory infiltration and levels of pro-inflammatory cytokines (IL-1, IL-6, TNF-), providing direct pharmacological evidence supporting the hypothesis that P2Y14R inhibition alleviates lung inflammation (Ma et al., 2025)