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Curcumin and endometrial carcinoma: an old spice as a novel agent

As a multimodal neuroregenerative agent, catalpol also targets the insulin-like growth factor-1 (IGF-1) signaling pathway to drive axonal repair and functional recovery post-stroke (Liu et al., 2025)

Specifically, in patients with acute cerebral ischemia, heightened peripheral levels of Tie2-expressing macrophages are strongly associated with improved clinical prognoses, implying that targeting these Tie2-high macrophages in the systemic circulation might constitute a pivotal mechanism mediating the brains intrinsic neuroprotective response (Sheng et al., 2021)