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As the key enzyme metabolizing APAP into NAPQI, cytochrome P450 enzymes are also considered to be intriguing target for the treatment of APAP-induced liver injury

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Consistently, GYY4137 treatment exhibited significant down-regulation of malondialdehyde content in LPS/ATP stimulated macrophages, which is commonly known as a marker of oxidative stress (Fig

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Overnight cultures grown into log phase, shaking at 200 rpm in liquid YPD, were used for each experiment

As revealed in Section 2.1, the ongoing research with respect to obtaining appropriate solutions for the use of cannabinoids for therapeutic purposes has resulted in the development of a wide range of formulations, with each one having its advantages and disadvantages