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Fibrinogen-Mimetic Nanoplatforms: Platelet-activatable nanoparticles (e.g., RGD-Chi@tPA) enhance thrombus targeting and tissue plasminogen activator penetration for efficient thrombolysis [110](Figure 6)

doi: 10.3390/nu10111805 60

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Notably, the contribution of the Gardos channels to eryptosis-associated cell shrinkage is supported by the fact that their inhibitors charybdotoxin and clotrimazole can avert cell shrinkage [78, 79]

By sensing tissue lactate, synovial T cells lose their mobility and are trapped in the tissue niche