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Subject: A "subject" may include a human subject for medical purposes, such as for the treatment of an existing disease, disorder, condition or the prophylactic for preventing the onset of a disease, disorder, or condition or an animal subject for medical, veterinary purposes, or developmental purposes

It has been shown that DDR components control NF-B signaling pathways in relation to DNA damage

Acrolein, at a fairly high concentrations (1001000 M), was shown to be a potent, time-dependent inactivator of protein tyrosine phosphatase-1B via covalent modification of an active site cysteine (Seiner et al

In an intriguing approach, carboplatin was examined in combination with mirvetuximab soravtansine in patients with platinum-sensitive ovarian cancer in a phase Ib trial (NCT02606305) [73]

Malignant tumors are a major threat to public health, with a high mortality rate and currently the second leading cause of death worldwide (Siegel et al

Nitric oxide modulates capillary formation at the endothelial cell-tumor cell interface