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ECM turnover The continuous process of ECM turnover is crucial for maintaining tissue homoeostasis and regulating mechanical changes, such as shear and stretch, along the intestinal wall [22]

Connective tissue growth factor (CTGF) also known as CCN2 appears to be a necessary cofactor for TGF- to activate or sustain extracellular matrix (ECM) production in both healthy and disease states [95]

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Not until was there no responses to the rat feet pinching, did the heart perfusion (injection from the left ventricle and liquid effusing via the right atrium) was initiated by normal saline (0.9%, 250ml, 40ml/min) and paraformaldehyde (4%, 500ml, 20ml/min), sequentially

145 ShibataS.WatanabeT.MatsumotoT.YunokiK.HorinouchiT.KirimotoH.et al (2022)

However, it provides the highest value for the greatest number of people looking for meaningful doses of betaine by itself