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PRODH is transcriptionally regulated by p53 and plays important roles in apoptosis, autophagy and cellular stress adaptation, particularly under nutrient deprivation or oxidative stress 61,62

Dorzagliatin in drug-nave patients with type 2 diabetes: a randomized, double-blind, placebo-controlled phase 3 trial

[DOI] [PMC free article] [PubMed] [Google Scholar] 119.Xu Q., Kanthasamy A.G., Reddy M.B

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Their results suggest that activation of CMA is involved in the execution of ferroptosis through GPX4 degradation in cell lines from different tissue origins [45]

& Sawtell, N