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The dispensability of ERO1A in healthy cells, in stark contrast with the relevance of ERO1A in TNBC, makes ERO1A an ideal target for TNBC therapy

[99] showed that medium-dose VitC (0.5 g kg 1 ) could abrogate cetuximab resistance in vivo and suggested sodium-dependent vitamin C transporter SVCT2 as a potental marker for enhancing efficacy of the combination treatment of VitC and cetuximab in KRAS-mutant CRC patients