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J Investig Med High Impact Case Rep 2024;12:23247096231224349

240 ToyotaY.IkedaM.ShinagawaS.MatsumotoT.MatsumotoN.HokoishiK.et al (2007)

Sample size determination

Cellular senescence in normal physiology

Recent studies exploring the possible cause-and-effect relationship between oxidative stress and diabetic nephropathy have demonstrated that the induction of a Nrf2-driven antioxidant response can ameliorate pathological manifestations of diabetic nephropathy in experimental animals whereas, conversely, the deletion of the Nrf2 gene can augment the severity of diabetic nephropathy (37)