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Another contributing factor could be that, in contrast to H 2 O 2 , which can cross membranes because it has only a small dipole moment and is therefore not very polar, about 50% of HOCl will be in the ionic hypochlorite form (ClO ) at the pH of the phagosome, which is not expected to cross the C

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14 : 18891900 Pineda-Molina E, Klatt P, Vazquez J, Marina A, Garcia de Lacoba M, Perez-Sala D and Lamas S (2001) Glutathionylation of the p50 subunit of NF-kappaB: a mechanism for redox-induced inhibition of DNA binding

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