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The spectrum of peptide therapy ranges from major FDA-approved prescription drugs such as insulin and GLP-1 analogues used to treat diabetes and metabolic disorders, to specialized, off-label compounds for weight management

It is known that interactions between Schwann cells and immune cells, particularly macrophages, in the disturbed injury microenvironment play critical roles in the whole process of nerve repair/regeneration following injury [6, 7]

Acknowledgements This work was supported by the German Research Foundation (DFG) SFB/TRR219 Project-ID 322900939 (S-03, C-04, M-03, M-05), SFB 1382 Project-ID 403224013 (A-04), by the CORONA foundation and by the Interreg V-A EMR program (EURLIPIDS, EMR23)

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& Sekmen, A

The hyperoxygenation of blood (pO 2 , at about 400 mmHg) is irrelevant because, during the 15-min infusion period, it mixes with venous blood so that the final venous pO 2 relative pressure is hardly modified