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Enzymatic hydrolysis within the stomach and small intestine rapidly cleaves peptide bonds, while epithelial tight junctions restrict paracellular transport of larger, hydrophilic molecules

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The non-oxygen-dependent Ru(II) complex has been used as a photosensitizer in treating hypoxic tumors

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Recent studies indicate that SGLT2i can mitigate early injury by improving renal hemodynamics and restoring mitochondrial function, exerting protective effects during the AKI-CKD progression through sustained anti-fibrotic actions [298]