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The expression of caspase-8 was increased in macrophages of lung tissue of monocroline-treated rats, which promoted inflammatory cell infiltration by activating the NLRP3/IL-1 signaling pathway [162]

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have found that oxidative stress (H 2 O 2 -induced) upregulates MST1 expression in RA-FLSs, triggering mitochondrial dysfunction and apoptosis (62)

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purification followed by immobilization)

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However, by virtue of stimulating the patient's immune white blood cells, ICI therapy sometimes causes serious side-effects that mimic autoimmune disease, including significant rash and/or inflammation of the thyroid, liver, lungs, nervous system, glandular system, heart, or other organs." The NCCN Guidelines for Patients are easy-to-understand, lay-language versions of the evidence-based, expert-consensus clinical practice guidelines used by health care providers all over the globe

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