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Furthermore, the original co-crystallized ligand inside the active site may affect the conformation of the protein and, as a consequence, the binding mode of other ligands

Trends Plant Sci 6:486492 Grabiska-Sota E, Winiowska E, Kalka J (2003) Toxicity of selected synthetic auxines 2, 4-D and MCPA derivatives to broad-leaved and cereal plants