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Injections are designed to be simple and performed at home

Some short-term studies in healthy older adults have been done with GHRH analogs like sermorelin or other secretagogues, and while they sometimes show increases in lean mass or decreases in fat mass, the improvements are modest and can be accompanied by side effects (e.g

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[DOI] [PubMed] [Google Scholar] 43.Venkataraman S., Hedrick J.L., Ong Z.Y., Yang C., Ee P.L.R., Hammond P.T., Yang Y.Y

The figure 25.3 % surpasses: Tirzepatide SURMOUNT-1: 22.5 % Semaglutide STEP-1: 14.9 % Retatrutide Phase 2: 24.2 % (comparable, but Phase 3 results for Retatrutide are still lacking) It raises the question whether CagriSema will be the first molecule with an effect truly comparable to bariatric surgery (typically 2530 % reduction)