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A: Side effects are rare and typically limited to mild injection site reactions such as redness or discomfort

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This AMPK-mediated inhibition of the TGF-1/Smad signaling pathway is reversed by the AMPK inhibitor Compound C in hepatocyte models, confirming the central role of this pathway ( Furthermore, silybin can disrupt the vicious cycle of liver fibrosis by regulating intercellular interactions

The past 5 years have seen foundational progress in this area, like ML models achieving quantitative predictions of tumor delivery efficiency (Mahdi et al., 2025)

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