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*Correspondence: Eng Wee Chua, [email protected] This article was submitted to Gastrointestinal and Hepatic Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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In the fatty acid (FA) synthesis pathway, ATP-citrate lyase (ATP-citrate lyase) generates acetyl-CoA from citrate, acetyl-CoA carboxylase (ACC) converts acetyl-CoA into malonyl-CoA, and fatty acid synthase (FASN) produces saturated FAs such as palmitate 12

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