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doi: 10.1016/S1567-4215(03)90130-5

Furthermore, -hydroxybutyrate serves as the primary source of acetyl-CoA in T cells, facilitating H3K27ac at promoters of effector gene loci (e.g., Ifng , Gzmb and Tbx21 ), thereby augmenting cytokine production in CD8 + T cells (e.g., IFN-, TNF-) and modulating cellular immune functions

By addressing these critical gaps, the translational potential of TCM-derived AMPK modulators in NAFLD management can be more rigorously evaluated

Seventeen metabolites differed significantly in dogs with DCM eating NT versus traditional diets (e.g., fatty acids, amino acids, legume biomarkers), suggesting different mechanisms for primary versus diet-associated DCM

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3333 mg