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Localised swelling or inflammation: In some cases, the area around the spasm may become swollen or inflamed due to the increased muscle activity and irritation

Biol Trace Elem Res 201 , 44294436 (2023)

Early identification and discontinuation of the causative agent are important

S-adenosyl methionine may worsen the symptoms of mania in people with bipolar disorder

Rather than relying on assumptions or genetic results alone, a more evidence-based approach is to assess functional biomarkers such as homocysteine and interpret these alongside the wider clinical picture

Since its very hard to get an accurate measure of B12 in people, the researchers instead searched for levels of methylmalonic acid (MMA) as its levels rise when B12 levels decrease