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The findings are interesting

In RPECs, GPX4 inhibitors such as 1s and 3R-RSL3 (RSL3) increase lysosome-associated membrane protein 2 (LAMP2) levels, leading to ferroptosis

8 BerneckerC.RagginerC.FaulerG.HorejsiR.MllerR.ZelzerS.et al (2011)

Tumor cell anti-oxidant defenses

Nrf2 is the master regulator of antioxidant defense, and impaired Nrf2 activation leads to mitochondrial damage [123]

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