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Description

The enzyme, ribonucleotide reductase, converts the diphosphate form of a ribose base to the deoxybase form

10.1016/j.mam.2005.07.003 4 AschnerM.GannonM.KimelbergH

doi: 10.1016/j.freeradbiomed.2021.02.039 103 BersukerKHendricksJMLiZMagtanongLFordBTangPHet al

While radiolabeled GSH has been extensively used to detect cellular uptake of GSH [5658], radiolabeling approaches can only provide a nonspecific readout of GSH metabolism based on the intracellular accumulation and/or proteome-wide incorporation of a specified radionuclide