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Description

Mailloux RJ, Jin X, and Willmore WG

The modified metabolites generated by phase I enzymes will further be modified by phase II conjugation enzymes, which are mostly transferase enzymes that can transfer the endogenous hydrophilic molecules to the metabolite to increase the solubility and promote excretion

doi: 10.1001/archneurol.2009.295 30

Research has also explored its potential to protect against neurodegenerative diseases, cancers, diabetes, and heart disease

Importantly, the serine thus produced can be converted to glycine via serine hydroxymethyltransferases concomitantly charging the folate pool with one-carbon units