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Description

LDH inhibition suppresses the lactylation of DNA repair proteins such as meiotic recombination 11-K673la (126) and Nijmegen breakage syndrome 1-K388la (34), impairing HR and enhancing chemosensitivity

This "blood sugar roller coaster" triggers the release of stress hormones like cortisol and adrenaline, which places an immense burden on an already dysregulated autonomic nervous system, often exacerbating symptoms of dysautonomia and POTS