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54 Notably, in addition to the consistent and antagonistic effects of aging and cancer, the paradoxical relationship between aging and cancer converges on two aging hallmarks: telomere shortening and cell senescence, which exert dual opposing effects on tumorigenesis

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10.2217/nnm-2022-0281 99 PappasA.JohnsenS.LiuJ

In general, deep lymphocytic infiltrates consisted mainly of CD3-positive cells whereas superficial lymphoid follicles contained a majority of CD3-negative B lymphocytes (Fig