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Published trial data suggests retatrutide GI adverse event rates at higher doses are broadly comparable to semaglutide

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30 , 31 , 32 , 33 The direct interaction between GSTP1 and STAT3 can promote HCC progression, 8 and our previous study found that GSTP1 could be ubiquitinated by FBX8, thus inhibiting its function in promoting CRC proliferation, invasion and metastasis