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Systemic adverse effects appear to be uncommon based on available reports, but comprehensive adverse event profiles are lacking due to the paucity of large-scale clinical investigations

Four hundred and thirty (88%) of these patients have conditions for which the drug is a proven benefit , so the increased frequency of injections accounts for most of the observed excess

2000 Sep;279(3):E501-7

It is an open-access article on genetic variants and adverse reactions to the smallpox vaccine

Research shows Vitamin B12 might help

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