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In individuals with overweight or obesity, treatment with semaglutide was associated with significant reductions in bodyweight, with a mean placebo-subtracted weight loss of 12.4% relative to placebo after 68 weeks reported in the STEP 1 trial

Morphologically, ferroptotic cells assume a characteristic rounded configuration akin to necrotic cells, although bereft of cytoplasmic or organelle engorgement and plasma membrane disruption

Behrendt, R., White, P

Studies in aging populations have examined whether growth hormone secretagogues may be associated with changes in hormone levels and body composition, with mixed results across different study designs

Graphical abstract Similar content being viewed by others Background Heart failure (HF) is commonly classified as HF with reduced ejection fraction (HFrEF) or HF with preserved ejection fraction (HFpEF)

Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles