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If you achieve meaningful weight loss in the first 12 weeks, that response pattern typically continues through long-term treatment

B12 is a complex vitamin, it does amazing work in the body, but it cant miraculously eek itself out over 3 months, it is excreted quickly as is the nature of all water soluble vitamins

Its onset is quick (pain relief often in a few minutes), and without epinephrine the effect typically lasts on the order of 3060 minutes for surgical anesthesia (longer if epinephrine is added)

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Once in the cell, the cellular enzymes release B12 from the receptor complex and it can enter the blood circulation