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Farnesyl pyrophosphate potentiates dendritic cell migration in autoimmunity through mitochondrial remodelling

CLASP2-Ser1025 phosphorylation regulates CLASPGolgi association and microtubule anchoring To explore the functional significance of Ser1025 phosphorylation in CLASP2, we constructed phosphorylation-mimetic (Ser1025Asp, S1025D) and non-phosphorylation-mimetic (Ser1025Ala, S1025A) mutants, together with wild-type (WT) CLASP2, and expressed them in HeLa cells (Figure 4A)

Sustained elevation of cortisol levels leads to atrophy of the hippocampus, hinders neurogenesis, and disturbs cognitive and emotional functions (28)

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Various exercise studies have observed improved endogenous defence in rodents following training [13,14,15,16,17], along with reduced ROS production at the same absolute exercise workload during following training [18]