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Further research has shown that activated ErbB2 stimulates GLS expression in breast cancer cells through the PI3K/Akt-independent NF-B pathway (197)

Dickstein DL, Kabaso D, Rocher AB, Luebke JI, Wearne SL, Hof PR (2007)

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In both genotypes, rhythmic plasma metabolites displayed a unimodal phase distribution with a broad peak around Zeitgeber time 0 (ZT0) (Figure 3I)

Furthermore, men with detectable CTCs and elevated methylated markers in plasma had a poorer prognosis than those with either marker alone (Okegawa et al, 2010)