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Cho SG, Lee YH, Park HS, Ryoo K, Kang KW, Park J et al

In addition, multi-omics big data integration genomic, transcriptomic, proteomic, metabolomic enables deeper insights into human variability in supplement metabolism and therapy efficacy that may realize personalized supplement strategies depending on tumour subtype, host biology under their life style (254)

& Menendez, J

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Various signals, including endoplasmic reticulum (ER) and oxidative stress and viral infection, activate ChaC1 promoters in different cell types, cellular processes and diseases through the unfolded protein response (UPR) (12,48,52)

It is ubiquitously present in mammalian cells and plays a central role in redox balance, cellular detoxification processes, and maintenance of intracellular thiol status