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The ARC contains neurons expressing key orexigenic neurotransmitters, agouti-related peptide (AgRP) and neuropeptide Y (NPY), as well as anorexigenic neurotransmitters, proopiomelanocortin (POMC) and cocaine- and amphetamine-regulated transcript (CART)

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Lancet 397:23612371 Martin T, Mikhael J, Hajek R, Kim K, Suzuki K, Hulin C et al (2020) Depth of response and response kinetics of isatuximab plus carfilzomib and dexamethasone in relapsed multiple myeloma: IKEMA interim analysis