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Acknowledgements This study was supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture of Japan, Japan Heart Foundation Grant for Research on Hypertension and Metabolism, and a Grant for Research Foundation for Community Medicine

Data are plotted as means SD, n = 4 biologically independent samples

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However, treatment with the fruit extract mitigated this effect, restoring HDAC2 expression levels to those comparable with the control group