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Flavonoids like quercetin have been found to enhance natural killer cells activity and stimulate macrophage phagocytosis hence strengthening innate immunity (Maheshwari et al., 2022)

Additionally, CBG demonstrates strong antagonistic activity at the 5-HT 1A receptor (Atalay et al., 2019), which contributes to reducing inflammation ( 2.2 Position of the regulatory agencies to the implementation of cannabinoids in clinical use The integration of cannabinoids into clinical practice is tightly regulated and must meet the same core regulatory requirements related to safety, efficacy, quality, and manufacturing standards as any other drug

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More important, their results revealed that ACN can significantly decrease MDA levels which is a biomarker for lipid peroxidation secondary to generation of ROS and reduce inflammation by preventing upregulation of pro-inflammatory cytokines, such as Interleukin 6 (IL-6), Interleukin 1b (IL-1b) and chemokine (C-X-C motif) receptor 2 (Cxcr2) (Donepudi et al., 2011)

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cell

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