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Notably, in MMTV-ErbB2 transgenic mice, the CSC subpopulation was most affected by CR, as shown by a reduction of luminal cells (CD24 high /CD49f low ), putative mammary reconstituting unit subpopulations (CD24 high /CD49f high ) and luminal progenitor cells (CD61 high /CD49f high )

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Nucleocytoplasmic shuttling of Smad proteins

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