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Isoform-specific activities of the regulatory subunits of phosphatidylinositol 3-kinases - potentially novel therapeutic targets

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Obesity alters both the protein composition and signaling effects of adipose-derived vesicles

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Contrary to most other leading causes of mortality, there is no effective treatment for AD and efforts to find effective treatments have met with limited success in part because the focus has been on testing drugs that target a specific pathogenic mechanism