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Description

Loren Pickart and colleagues isolated a short peptide from human plasma that extended the lifespan of cultured liver cells. They identified its sequenceglycyl-histidyl-lysine (GHK)and discovered that when bound to copper ions, it formed GHK-Cu, a complex with strong biological activity in cell growth and tissue repair

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Novel applications, including antioxidants in cancer-related fertility care and cryopreservation, are considered

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It is also very necessary to identify if TMAO contributes to chondrocytes injury through modulating the classical pathways of ferroptosis such as ACSL4/GPX4 or other specific pathways, such as those of iron-related proteins, lipid peroxidation products, and other sensitivities to mechanical stimulation

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Hiddemann W, Buechner T, Andreeff M , Woermann B, Clarkson BD

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Kantidakis, T., Ramsbottom, B

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K.LightmanS

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