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By the subsequent action of CPT-I on the outer surface of the outer mitochondrial membrane, the carnitine carrier and CPT-II on the inner surface of the inner mitochondrial membrane, palmitoyl-CoA virtually is transported into the matrix, but note that its CoASH comes from the matrix space, while initially the CoASH is from the cytosol

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PMC4684116 Sekhar RV, Patel SG, Guthikonda AP, et al

Potter GB, Zarach JM, Sisk JM, Thompson CC (2002) The thyroid hormone-regulated corepressor hairless associates with histone deacetylases in neonatal rat brain