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XXVIII Brazilian Congress of Head and Neck Surgery

The expression and activities of GPX3 are changed in many pathological processes involved in systemic non-neoplastic disorders, such as kidney diseases, cardiovascular diseases, respiratory diseases, metabolic diseases, digestive system diseases, neurological disorders, bone and joint diseases, and other diseases (Figure 3)

10.3389/fnut.2022.857879 Front Nutr

Therefore, GPX4-mediated ferroptosis may be a promising target for treating major depressive disorder

have reported that low levels of frataxin leads to the reduced expression of NRF2 and antioxidants present in the dorsal root ganglia of FRDA mouse models (Shan et al., 2013)

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