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For patients seeking weight loss who request B12 injections, GPs should: Assess for genuine deficiency through appropriate blood tests rather than empirical treatment Provide education about the lack of evidence supporting B12 for weight loss in non-deficient individuals Explore underlying concerns about weight and energy levels, addressing these through appropriate channels Signpost to evidence-based resources such as NHS weight management services according to local pathways Patients should contact their GP if they experience unexplained fatigue, neurological symptoms (numbness, tingling, balance problems), or signs of anaemia (pallor, breathlessness, palpitations), as these may indicate B12 deficiency requiring investigation

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It's beneficial for everyone, especially those following a plant-based or restricted diet as the main source of Vitamin B12 in food comes from meat, fish, eggs and cheese

Another reasonable trigger point is when you reach a body fat percentage where the remaining fat is concentrated in specific areas rather than distributed evenly