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The Effects of a Single Oral Dose of Pyridoxine on Alpha-Aminoadipic Semialdehyde, Piperideine-6-Carboxylate, Pipecolic Acid, and Alpha-Aminoadipic Acid Levels in Pyridoxine-Dependent Epilepsy. Frontiers in Pediatrics, vol

In general, an increase in the pH weakens the hydrophobic interaction probably due to an increased titration of charged groups, thereby leading to an increase of protein hydrophilicity

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In this review, we update the current knowledge on cysteine modifications and their consequences in pancreatic -cells

This 'first-pass effect' exposes the compound to hepatic enzymes

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