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Symptoms frequently begin or worsen during periods of significant hormonal changes, predominantly at puberty (15.767.3%), but also during pregnancy/lactation (9.563.1%), menopause (1.921%), or with the use of exogenous hormones like oral contraceptives (1.23.8%) 16

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Similar content being viewed by others Introduction Gastric cancer (GC) stands as a highly aggressive and life-threatening malignancy, posing a robust risk to global health and ranking as the fourth most common cause of cancer-related fatalities worldwide [1]

GH and IGF-1 are related but not identical: GH has stronger direct effects on fat metabolism, while IGF-1 is more directly linked to tissue growth and repair signaling

20241112), State Key Laboratory of Traditional Chinese Medicine Syndrome (QZ2023ZZ11), Chinese Medicine Guangdong Laboratory (HQL2024PZ005), the 2025 Annual Basic and Applied Fundamental Research Topics-Young Doctor Launch Program (2025A04J4194), and Postdoctoral Research Project of the Second Affiliated Hospital of Guangzhou University of Chinese Medicine (No

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